Cbd oil and methotrexate. Plaquenil is a prescription drug that’s used for rheumatoid arthritis, malaria, and lupus. 9% Diamonds, Delta-9 Gummies & a Complete Therapeutic Arsenal, Featured by ABC13 News & Backed by 7+ University Studies, Born from the 10-Year Miracle of Bentley the Paralyzed Dog, Farm That night began a journey from cannabis dealer to cannabis scientist. 9% THCa Diamonds, Delta-9 Gummies & Edibles, Validated by ABC13 Houston and 7+ University Research Evidence-based interaction details between Methotrexate Sodium (brand name (s): Xatmep) and Cannabis, including interaction severity and how likely the interaction is to occur. | Find, read and cite all the research you A phase IV clinical study of FDA data: drug interactions are found among 1,307 people who take Cannabis (marijuana) and Methotrexate (methotrexate sodium). Animal studies and in vitro experiments suggest immune modulatory and anti-inflammatory properties of cannabinoids, which makes them possible candidates for therapy of autoimmune diseases (reviewed in [46]). Read about the more serious and most common methotrexate interactions here. Hi, I’ve been taking cbd oil for 4 months and with some of my meds I have to leave a 4-hour gap and 2-hours with others. Aug 22, 2025 · Learn about the important medical considerations and potential interactions when combining CBD oil with Methotrexate. The drug and preparations of it (e. A moderate drug interaction exists between Cannabidiol and Methotrexate. Read about their experiences and learn more about CBD oils. 9% THCa Diamonds, Delta-9 Gummies, and a Complete Therapeutic Arsenal - Featured by ABC13 Houston and Validated by 7+ University Studies Including Methotrexate (MTX) is an antineoplastic agent and has neurotoxic effects. Unlike tetrahydrocannabinol (THC), CBD is non-intoxicating and non-psychoactive, making it an attractive option for therapeu Learn how medical cannabis may help relieve arthritis pain and inflammation safely under healthcare guidance. 9% THCa Diamonds & Concentrates, Delta-9 Gummies, and a Complete Therapeutic Arsenal - Research-Validated by Johns Hopkins & WSU, Formulas Born from the Bentley 10-Year Miracle Story, All You may be wondering if marijuana may ease the pain and discomfort from rheumatoid arthritis. I've been on MTX for almost 2 months I take the shot once a week ( -_- ) and on CBD oil for a while I haven't noticed any side effects. Cannabidiol (CBD), one of over 100 phytocannabinoids found in the Cannabis sativa plant, has gained significant attention due to its therapeutic potential and relatively favorable safety profile. Methotrexate can interact with NSAIDs and certain antibiotics. Cannabidiol (CBD), known for its antioxidant and anti- Cbd oil and methotrexate Hi, I’ve been taking cbd oil for 4 months and with some of my meds I have to leave a 4-hour gap and Morning everyone I take Methotrexate and would like to know if anyone on here is taking it, and takes CBD oil . g. Learn more about CBD interactions with drugs and how to stay safe when you use CBD for pain or other symptoms. Evidence-based interaction details between Methotrexate (brand name (s): Rheumatrex, Otrexup, Rasuvo, Reditrex) and Cannabis, including interaction severity and how likely the interaction is to occur. Little River County Cannabis Revolution: OilWell Cannabis Now Delivers Houston's World-Exclusive Legal THCa Rick Simpson Oil with Revolutionary Dual-Pathway Technology, 16,590mg Full-Spectrum Formulations, 50+ Premium Indoor THCa Flower Strains, 99. Discover how CBD oil interacts with commonly prescribed rheumatology drugs and the implications for patient care. Explore the best CBD products for joint pain relief, read our tester experiences, and learn how to shop for the best CBD products for your needs here. You may be wondering if marijuana may ease the pain and discomfort from rheumatoid arthritis. We developed a specific CBD Golden Paste formula—1/2 cup organic turmeric, 1 cup water, 1/3 cup coconut oil, 1-2 tsp black pepper, and precisely dosed CBD oil—and administered it with the precision of a chemist. Thanks! Hi! I am on 15mg injectable methotrexate (Ebetrexat) weekly for ankylosing spondylitis and am wondering if it interacts with CBD resin/oil. Cannabidiol, or CBD, is a chemical compound in cannabis with a variety of uses. Can it replace or bolster antibiotics? This article answers whether you can take antibiotics alongside CBD products. Rheumatology key message. Recently, there has been increased interest in CBD, as several studies showed promising anticonvulsant efficacy with few side effects. Methotrexate (MTX) is an antineoplastic agent and has neurotoxic effects. I have asked my doctor and pharmacy if I can take it, but they won’t commit themselves Severe Methotrexate Interactions Methotrexate is known to cause severe drug interactions when taken with many types of medications. 3 Those taking methotrexate should be aware of the drug interactions and speak with their healthcare provider about the drugs or supplements they are taking prior to starting treatment with methotrexate. Explore our Treatment & Prevention page, your guide to tailored care such as medication, surgery, and pain relief to live better. Cannabidiol (CBD), known for its antioxidant and anti-inflammatory properties, was investigated for its potential protective effects against MTX-induced lu … A phase IV clinical study of FDA data: drug interactions are found among 1,307 people who take Cannabis (marijuana) and Methotrexate (methotrexate sodium). The aim of this study is to examine the p … Methotrexate (MTX) is a widely used medication for various cancers, yet its use is associated with adverse effects on organs, notably the lungs. I started back on methotrexate injections last week, didn’t have my cbd oil Hi there, Does anyone here take CBD oil/capsules while on Methotrexate? I'm concerned that the two may interact and affect the liver and was wondering if anyone had anecdotal experience either way. Concomitant use of cannabidiol oil with steroids, naproxen, tramadol and amitriptyline can potentiate adverse events. Carbamazepine (Tegretol), an anticonvulsant, and prednisone, a corticosteroid, have the same effect on cannabidiol. 9% THCa Diamonds, Artisan Concentrates & Delta-9 Gummies – Born from the 10-Year Miracle That Saved a Paralyzed Dog, Backed by 7+ Peer-Reviewed Methotrexate (MTX) is a widely used medication for various cancers, yet its use is associated with adverse effects on organs, notably the lungs. I was taking CBD oil for neuropathy pain before I was diagnosed with RA. Cannabidiol, a non-intoxicating phytocannabinoid, has potential therapeutic effects over a broad range of disorders. . It exerts its toxic effect on the brain by triggering inflammation and apoptosis. Cannabidiol (CBD), known for its antioxidant and anti-inflammatory properties, was investigated for its potential protective effects against MTX-induced lu … Union County Cannabis and Health Revolution: OilWell Cannabis, Houston's ABC13-Featured Pioneer, Brings You the World's ONLY Legal THCa Rick Simpson Oil (16,590mg RSO), 50+ Premium THCa Flower Strains, 99. Here are 6 benefits of CBD oil. Cannabidiol (CBD), known for its antioxidant and anti- I've been on MTX for almost 2 months I take the shot once a week ( -_- ) and on CBD oil for a while I haven't noticed any side effects. Cannabinoids have gained popularity recently with special emphasis on their use for chronic pain. Nov 21, 2025 · CBD and methotrexate should not be combined without medical supervision due to a significant risk of increased liver toxicity. PDF | Methotrexate (MTX) is a widely used medication for various cancers, yet its use is associated with adverse effects on organs, notably the lungs. The methotrexate dosage is taken weekly and not daily like most other medications. Blekinge County, Earth, Europe, Sweden Blekinge County Cannabis Revolution: OilWell Cannabis Introduces Houston’s ABC13-Featured, World-Exclusive THCa Rick Simpson Oil (16,590mg, The Only Legal RSO), 50+ Premium Therapeutic THCa Flower Strains, 99. The aim of this study is to examine the p … Rheumatology key message. This does not mean the potential for an interaction does not exist, however. What drugs should not be taken with CBD and what can you do to avoid them? CBD oil has been shown to kill treatment-resistant bacteria. , oil extracts) gain popularity among RA [43], osteoarthritis [44], and IBD [45] patients. Cannabidiol (CBD), derived from hemp, possesses antioxidant, anti-inflammatory CBD interactions are a top concern among those already on medication. Learn how medical cannabis may help relieve arthritis pain and inflammation safely under healthcare guidance. Cannabidiol (CBD), known for its antioxidant and anti-inflammatory properties, was investigated for its potential protective effects against MTX-induced lung injury. Learn about possible interactions with other drugs, alcohol, and more. Our editors tested CBD oils for managing pain. Methotrexate (MTX) is a widely used medication for various cancers, yet its use is associated with adverse effects on organs, notably the lungs. Veles Cannabis Authority: OilWell Cannabis Introduces the World's ONLY Legal THCa Rick Simpson Oil from Houston - 16,590mg Full-Spectrum RSO with Dual-Pathway Technology, 50+ Premium THCa Flower Strains, 99. It is vital to take it properly and understand why. Here’s what to know. Our guide explores the seven best CBD products to help ease the pain associated with arthritis. Brittany Region, Earth, Europe, France Brittany Region Premium Cannabis Authority: OilWell Cannabis Brings Houston’s Revolutionary Legal THCa Rick Simpson Oil to Brittany – The World’s Only Legal RSO with 16,590mg & Dual-Pathway Technology, Featuring 50+ Therapeutic THCa Flower Strains, 99. Both substances are processed by the same liver enzymes, creating a potential for dangerous drug interactions and elevated levels of methotrexate in the body. View detailed information regarding this drug interaction. Brown and Winterstein (2019) [6] suggested that CBD may interact with methotrexate treatment because it inhibits the ABCG2/BCRP transporter [24], which contributes to cellular efflux of methotrexate [43]. Here we explain what drugs shouldn’t be taken with CBD — and when to consult your doctor if you’re not sure about the potential interactions. The Fast Facts Growing research on CBD oil for joint and arthritis pain suggests it may help. Although NICE guidelines advise against their usage for management of chronic pain, almost all rheumatologists encounter a few patients in their daily Drugs That Decrease the Benefits of CBD Oil Although there are little or no drug interactions between CBD oil and antibiotics, rifampin (Rifadin, Rimactane) is known to decrease the effect of CBD on the body. Methotrexate (MTX), a widely used chemotherapeutic agent, often induces hepatotoxicity, limiting its clinical utility. I've taken CBD before and had a good experience but now I'm not sure if they should be taken together and there is not much information on the Internet. Is it safe to take CBD and methotrexate together? Safety appears acceptable at typical consumer CBD doses (≤30 mg per day) for most adults, provided liver function is normal and no other CYP‑interacting medications are used. Cannabidiol (CBD), known for its antioxidant and anti- Learn about the important medical considerations and potential interactions when combining CBD oil with Methotrexate. Jun 22, 2023 · When you take CBD alongside certain medications, it can trigger negative drug interactions. In 2018, a CBD-based oral solution, Epidiolex®, was approved by the FDA to treat two severe forms of pediatric epilepsy, Dravet syndrome, and Therefore, we provide an overview of the scientific work on cannabinoids, CBD, and hemp oil and clarify the distinction between marijuana, hemp, and the different components of CBD and hemp oil products so that clinicians may be able to direct their patients to the safest and most evidence-based products. Explore effective treatments for rheumatoid arthritis, including medications, therapy, and lifestyle changes for better joint health. Cannabidiol (CBD) is an agent known for its antioxidant, anti-inflammatory effects in various tissues. Aug 24, 2025 · There were no interactions found between Methotrexate and Cannabis. ph0dr, evla, o5lcs, ahlo, vhkrdy, 32afoo, jejh, z577r, 8r3k9, e1vf8,